m5ad.16xlarge

General purpose · m5ad series · AMD EPYC 7571

vCPU
64
Memory
256 GiB
Linux / hour
$3.30
Per month
$2,406
Per vCPU-hour
$0.0515
Per GiB-hour
$0.0129

Analysis

The m5ad.16xlarge is a general purpose instance in the m5ad series with 64 vCPUs and 256 GiB of memory on AMD EPYC 7571 (up to 2.5 GHz), which makes it balanced at 4 GiB of memory per vCPU.

Within the same generation and size, the m5a.16xlarge on AMD EPYC 7571 costs $2.75/hour, 17% less ($397 a month). The other variants are the m5.16xlarge at $3.07, the m5d.16xlarge at $3.62 and the m5n.16xlarge at $3.81.

Running it in Mumbai instead of São Paulo saves $2,287 a month per instance: $2.15/hour against $5.28/hour, a 146% spread.

On demand it costs $3.30/hour in US East (N. Virginia), $2,406 a month if left running, which puts it mid-table for general purpose types at the 41st percentile per vCPU ($0.0515 per vCPU-hour) and the 41st percentile per GiB ($0.0129 per GiB-hour).

It has local instance storage (4 x 600 GB NVMe SSD), which is fast but lost when the instance stops. Network: 12 Gigabit.

Looking beyond its own line, 13 of 35 current types with 64 vCPUs and similar memory are cheaper. The cheapest of those is the m6g.16xlarge on AWS Graviton2 at $2.46/hour.

Reserving it for a year with no upfront payment cuts the Linux rate to $2.08/hour, which beats on demand once it runs more than 63% of the time; three years brings it to $1.42/hour, 57% below on demand. Windows Server roughly adds 89% to the bill at $6.24/hour, because the licence is charged per vCPU.

Price by region (USD per hour)

RegionLinuxWindows1-yr RI3-yr RI
N. Virginia us-east-1$3.30$6.24$2.08$1.42
Ohio us-east-2$3.30$6.24$2.08$1.42
Oregon us-west-2$3.30$6.24$2.08$1.42
Canada Central ca-central-1$3.68$6.62$2.32$1.59
São Paulo sa-east-1$5.28$8.22$3.21$2.28
Ireland eu-west-1$3.68$6.62$2.32$1.59
London eu-west-2$3.84$6.78$2.42$1.66
Frankfurt eu-central-1$4.00$6.94$2.52$1.73
Mumbai ap-south-1$2.15$5.09$1.35$0.9280
Singapore ap-southeast-1$4.13$7.07$2.60$1.78
Sydney ap-southeast-2$4.16$7.10$2.62$1.80
Tokyo ap-northeast-1$4.29$7.23$2.70$1.85

Shared tenancy, no pre-installed software. Reserved rates are standard, no upfront, per hour. Prices as of 2026-11-04.

Same shape, other types

TypevCPUMemory$/hourvs m5ad.16xlarge
m6g.16xlarge
AWS Graviton2 Processor
64256 GiB$2.46-25%
m7g.16xlarge
AWS Graviton3 Processor
64256 GiB$2.61-21%
m5a.16xlarge
AMD EPYC 7571
64256 GiB$2.75-17%
m6a.16xlarge
AMD EPYC 7R13 Processor
64256 GiB$2.76-16%
m8g.16xlarge
AWS Graviton4 Processor
64256 GiB$2.87-13%
m6gd.16xlarge
AWS Graviton2 Processor
64256 GiB$2.89-12%

Cost calculator

Specs

vCPU64
Memory256 GiB (4.0 per vCPU)
ProcessorAMD EPYC 7571
Clock2.5 GHz
Storage4 x 600 NVMe SSD
Network12 Gigabit

m5ad sizes

m5ad.large2 vCPU$0.1030
m5ad.xlarge4 vCPU$0.2060
m5ad.2xlarge8 vCPU$0.4120
m5ad.4xlarge16 vCPU$0.8240
m5ad.8xlarge32 vCPU$1.65
m5ad.12xlarge48 vCPU$2.47
m5ad.16xlarge64 vCPU$3.30
m5ad.24xlarge96 vCPU$4.94