p5.4xlarge

GPU instance · p5 series · AMD EPYC 7R13 Processor

vCPU
16
Memory
256 GiB
Linux / hour
$6.88
Per month
$5,022
Per vCPU-hour
$0.4300
Per GiB-hour
$0.0269

Analysis

The p5.4xlarge is a gpu instance instance in the p5 series with 16 vCPUs and 256 GiB of memory on AMD EPYC 7R13 (up to 2.95 GHz), which makes it very memory-heavy at 16 GiB of memory per vCPU.

Running it in N. Virginia instead of São Paulo saves $3,415 a month per instance: $6.88/hour against $11.56/hour, a 68% spread. It is not offered in Canada Central, Ireland and Singapore, so plan around that if you need a presence there.

It carries 1 GPU with 80 GB HBM3 of GPU memory, so most of the price is the accelerator rather than the CPUs. It has local instance storage (1 x 3840 GB SSD), which is fast but lost when the instance stops. Network: 100 Gigabit.

Per vCPU it is one of the dearer gpu instance types: 96% of the 78 current types in the family cost less than its $0.4300 per vCPU-hour. The premium mostly pays for the accelerators. On demand it is $6.88/hour in US East (N. Virginia), or $5,022 for a 730-hour month.

It is the smallest of the 2 p5 sizes. Stepping up to the p5.48xlarge gives 192 vCPUs and 2048 GiB for $35,157 more a month. Unit price is not flat across the series ($0.2867 to $0.4300 per vCPU-hour), so the size changes the rate you pay.

Price by region (USD per hour)

RegionLinuxWindows1-yr RI3-yr RI
N. Virginia us-east-1$6.88$7.62–$2.97
Ohio us-east-2$6.88$7.62–$2.97
Oregon us-west-2$6.88$7.62–$2.97
São Paulo sa-east-1$11.56$12.29–$4.99
London eu-west-2$8.94$9.68–$3.86
Frankfurt eu-central-1$8.60$9.34––
Mumbai ap-south-1$8.26$8.99–$3.57
Sydney ap-southeast-2$8.94$9.68–$3.86
Tokyo ap-northeast-1$8.60$9.34–$3.72

Shared tenancy, no pre-installed software. Reserved rates are standard, no upfront, per hour. Prices as of 2026-11-04.

Cost calculator

Specs

vCPU16
Memory256 GiB (16.0 per vCPU)
ProcessorAMD EPYC 7R13 Processor
Clock2.95 GHz
GPUs1 · 80 GB HBM3
Storage1 x 3840 GB SSD
Network100 Gigabit

p5 sizes

p5.4xlarge16 vCPU$6.88
p5.48xlarge192 vCPU$55.04