r5.16xlarge

Memory optimized · r5 series · Intel Xeon Platinum 8175

vCPU
64
Memory
512 GiB
Linux / hour
$4.03
Per month
$2,943
Per vCPU-hour
$0.0630
Per GiB-hour
$0.00788

Analysis

The r5.16xlarge is a memory optimized instance in the r5 series with 64 vCPUs and 512 GiB of memory on Intel Xeon Platinum 8175 (up to 3.1 GHz), which makes it memory-heavy at 8 GiB of memory per vCPU.

Within the same generation and size, the r5a.16xlarge on AMD EPYC 7571 costs $3.62/hour, 10% less ($304 a month). The other variants are the r5ad.16xlarge at $4.19, the r5d.16xlarge at $4.61 and the r5n.16xlarge at $4.77.

At $4.03/hour on demand in US East (N. Virginia), about $2,943 a month, the r5.16xlarge is one of the cheaper ways to buy memory optimized capacity: only 16% of the 385 current memory optimized types cost less per vCPU-hour than its $0.0630.

Running it in N. Virginia instead of São Paulo saves $1,752 a month per instance: $4.03/hour against $6.43/hour, a 60% spread.

It is 5.3% cheaper than the older r4.16xlarge on Intel Xeon E5-2686 v4 (Broadwell), so staying on the previous generation costs more as well as being slower.

Looking beyond its own line, 6 of 39 current types with 64 vCPUs and similar memory are cheaper. The cheapest of those is the r6g.16xlarge on AWS Graviton2 at $3.23/hour.

Reserving it for a year with no upfront payment cuts the Linux rate to $2.54/hour, which beats on demand once it runs more than 63% of the time; three years brings it to $1.74/hour, 57% below on demand. Windows Server roughly adds 73% to the bill at $6.98/hour, because the licence is charged per vCPU.

Price by region (USD per hour)

RegionLinuxWindows1-yr RI3-yr RI
N. Virginia us-east-1$4.03$6.98$2.54$1.74
Ohio us-east-2$4.03$6.98$2.54$1.74
Oregon us-west-2$4.03$6.98$2.54$1.74
Canada Central ca-central-1$4.42$7.36$2.78$1.91
São Paulo sa-east-1$6.43$9.38$4.05$2.78
Ireland eu-west-1$4.51$7.46$2.84$1.95
London eu-west-2$4.74$7.68$2.98$2.05
Frankfurt eu-central-1$4.86$7.81$3.06$2.10
Mumbai ap-south-1$4.16$7.10$2.61$1.80
Singapore ap-southeast-1$4.86$7.81$3.06$2.10
Sydney ap-southeast-2$4.83$7.78$3.04$2.09
Tokyo ap-northeast-1$4.86$7.81$3.06$2.10

Shared tenancy, no pre-installed software. Reserved rates are standard, no upfront, per hour. Prices as of 2026-11-04.

Same shape, other types

TypevCPUMemory$/hourvs r5.16xlarge
r6g.16xlarge
AWS Graviton2 Processor
64512 GiB$3.23-20%
r7g.16xlarge
AWS Graviton3 Processor
64512 GiB$3.43-15%
r5a.16xlarge
AMD EPYC 7571
64512 GiB$3.62-10%
r6a.16xlarge
AMD EPYC 7R13 Processor
64512 GiB$3.63-10%
r6gd.16xlarge
AWS Graviton2 Processor
64512 GiB$3.69-9%
r8g.16xlarge
AWS Graviton4 Processor
64512 GiB$3.77-6%

Cost calculator

Specs

vCPU64
Memory512 GiB (8.0 per vCPU)
ProcessorIntel Xeon Platinum 8175
Clock3.1 GHz
StorageEBS only
Network20 Gigabit

r5 sizes

r5.large2 vCPU$0.1260
r5.xlarge4 vCPU$0.2520
r5.2xlarge8 vCPU$0.5040
r5.4xlarge16 vCPU$1.01
r5.8xlarge32 vCPU$2.02
r5.12xlarge48 vCPU$3.02
r5.16xlarge64 vCPU$4.03
r5.24xlarge96 vCPU$6.05