m5dn.16xlarge
General purpose · m5dn series · Intel Xeon Platinum 8259 (Cascade Lake)
- vCPU
- 64
- Memory
- 256 GiB
- Linux / hour
- $4.35
- Per month
- $3,177
- Per vCPU-hour
- $0.0680
- Per GiB-hour
- $0.0170
Analysis
The m5dn.16xlarge is a general purpose instance in the m5dn series with 64 vCPUs and 256 GiB of memory on Intel Xeon Platinum 8259 (Cascade Lake) (up to 3.1 GHz), which makes it balanced at 4 GiB of memory per vCPU.
Within the same generation and size, the m5a.16xlarge on AMD EPYC 7571 costs $2.75/hour, 37% less ($1,168 a month). The other variants are the m5.16xlarge at $3.07, the m5ad.16xlarge at $3.30 and the m5d.16xlarge at $3.62.
Running it in N. Virginia instead of Tokyo saves $911 a month per instance: $4.35/hour against $5.60/hour, a 29% spread. It is not offered in Canada Central, São Paulo, London, Mumbai and Sydney, so plan around that if you need a presence there.
On demand it costs $4.35/hour in US East (N. Virginia), $3,177 a month if left running, which puts it mid-table for general purpose types at the 71st percentile per vCPU ($0.0680 per vCPU-hour) and the 71st percentile per GiB ($0.0170 per GiB-hour).
Looking beyond its own line, 25 of 35 current types with 64 vCPUs and similar memory are cheaper. The cheapest of those is the m6g.16xlarge on AWS Graviton2 at $2.46/hour.
It has local instance storage (4 x 600 GB NVMe SSD), which is fast but lost when the instance stops. Network: 75 Gigabit.
Price by region (USD per hour)
| Region | Linux | Windows | 1-yr RI | 3-yr RI | |
|---|---|---|---|---|---|
| N. Virginia us-east-1 | $4.35 | $7.30 | $2.74 | $1.69 | |
| Ohio us-east-2 | $4.35 | $7.30 | $2.74 | $1.69 | |
| Oregon us-west-2 | $4.35 | $7.30 | $2.74 | $1.69 | |
| Ireland eu-west-1 | $4.86 | $7.81 | $3.06 | $2.10 | |
| Frankfurt eu-central-1 | $5.18 | $8.13 | $3.27 | $2.24 | |
| Singapore ap-southeast-1 | $5.34 | $8.29 | $3.37 | $2.11 | |
| Tokyo ap-northeast-1 | $5.60 | $8.54 | $3.53 | $2.42 |
Shared tenancy, no pre-installed software. Reserved rates are standard, no upfront, per hour. Prices as of 2026-11-04.
Same shape, other types
| Type | vCPU | Memory | $/hour | vs m5dn.16xlarge |
|---|---|---|---|---|
| m6g.16xlarge AWS Graviton2 Processor | 64 | 256 GiB | $2.46 | -43% |
| m7g.16xlarge AWS Graviton3 Processor | 64 | 256 GiB | $2.61 | -40% |
| m5a.16xlarge AMD EPYC 7571 | 64 | 256 GiB | $2.75 | -37% |
| m6a.16xlarge AMD EPYC 7R13 Processor | 64 | 256 GiB | $2.76 | -36% |
| m8g.16xlarge AWS Graviton4 Processor | 64 | 256 GiB | $2.87 | -34% |
| m6gd.16xlarge AWS Graviton2 Processor | 64 | 256 GiB | $2.89 | -34% |
Cost calculator
Specs
| vCPU | 64 |
|---|---|
| Memory | 256 GiB (4.0 per vCPU) |
| Processor | Intel Xeon Platinum 8259 (Cascade Lake) |
| Clock | 3.1 GHz |
| Storage | 4 x 600 NVMe SSD |
| Network | 75 Gigabit |
m5dn sizes
| m5dn.large | 2 vCPU | $0.1360 |
| m5dn.xlarge | 4 vCPU | $0.2720 |
| m5dn.2xlarge | 8 vCPU | $0.5440 |
| m5dn.4xlarge | 16 vCPU | $1.09 |
| m5dn.8xlarge | 32 vCPU | $2.18 |
| m5dn.12xlarge | 48 vCPU | $3.26 |
| m5dn.16xlarge | 64 vCPU | $4.35 |
| m5dn.24xlarge | 96 vCPU | $6.53 |