m5dn.4xlarge

General purpose · m5dn series · Intel Xeon Platinum 8259 (Cascade Lake)

vCPU
16
Memory
64 GiB
Linux / hour
$1.09
Per month
$794
Per vCPU-hour
$0.0680
Per GiB-hour
$0.0170

Analysis

The m5dn.4xlarge is a general purpose instance in the m5dn series with 16 vCPUs and 64 GiB of memory on Intel Xeon Platinum 8259 (Cascade Lake) (up to 3.1 GHz), which makes it balanced at 4 GiB of memory per vCPU.

Within the same generation and size, the m5a.4xlarge on AMD EPYC 7571 costs $0.6880/hour, 37% less ($292 a month). The other variants are the m5.4xlarge at $0.7680, the m5ad.4xlarge at $0.8240 and the m5d.4xlarge at $0.9040.

Running it in N. Virginia instead of Tokyo saves $228 a month per instance: $1.09/hour against $1.40/hour, a 29% spread. It is not offered in Canada Central, São Paulo, London, Mumbai and Sydney, so plan around that if you need a presence there.

On demand it costs $1.09/hour in US East (N. Virginia), $794 a month if left running, which puts it mid-table for general purpose types at the 71st percentile per vCPU ($0.0680 per vCPU-hour) and the 71st percentile per GiB ($0.0170 per GiB-hour).

Looking beyond its own line, 25 of 37 current types with 16 vCPUs and similar memory are cheaper. The cheapest of those is the m6g.4xlarge on AWS Graviton2 at $0.6160/hour.

It has local instance storage (2 x 300 GB NVMe SSD), which is fast but lost when the instance stops. Network: Up to 25 Gigabit.

Price by region (USD per hour)

RegionLinuxWindows1-yr RI3-yr RI
N. Virginia us-east-1$1.09$1.82$0.6850$0.4230
Ohio us-east-2$1.09$1.82$0.6850$0.4230
Oregon us-west-2$1.09$1.82$0.6850$0.4230
Ireland eu-west-1$1.22$1.95$0.7660$0.5250
Frankfurt eu-central-1$1.30$2.03$0.8160$0.5600
Singapore ap-southeast-1$1.34$2.07$0.8420$0.5270
Tokyo ap-northeast-1$1.40$2.14$0.8820$0.6050

Shared tenancy, no pre-installed software. Reserved rates are standard, no upfront, per hour. Prices as of 2026-11-04.

Same shape, other types

TypevCPUMemory$/hourvs m5dn.4xlarge
m6g.4xlarge
AWS Graviton2 Processor
1664 GiB$0.6160-43%
m7g.4xlarge
AWS Graviton3 Processor
1664 GiB$0.6528-40%
m5a.4xlarge
AMD EPYC 7571
1664 GiB$0.6880-37%
m6a.4xlarge
AMD EPYC 7R13 Processor
1664 GiB$0.6912-36%
m8g.4xlarge
AWS Graviton4 Processor
1664 GiB$0.7181-34%
m6gd.4xlarge
AWS Graviton2 Processor
1664 GiB$0.7232-34%

Cost calculator

Specs

vCPU16
Memory64 GiB (4.0 per vCPU)
ProcessorIntel Xeon Platinum 8259 (Cascade Lake)
Clock3.1 GHz
Storage2 x 300 NVMe SSD
NetworkUp to 25 Gigabit

m5dn sizes

m5dn.large2 vCPU$0.1360
m5dn.xlarge4 vCPU$0.2720
m5dn.2xlarge8 vCPU$0.5440
m5dn.4xlarge16 vCPU$1.09
m5dn.8xlarge32 vCPU$2.18
m5dn.12xlarge48 vCPU$3.26
m5dn.16xlarge64 vCPU$4.35
m5dn.24xlarge96 vCPU$6.53