r5dn.12xlarge

Memory optimized · r5dn series · Intel Xeon Platinum 8259 (Cascade Lake)

vCPU
48
Memory
384 GiB
Linux / hour
$4.01
Per month
$2,926
Per vCPU-hour
$0.0835
Per GiB-hour
$0.0104

Analysis

The r5dn.12xlarge is a memory optimized instance in the r5dn series with 48 vCPUs and 384 GiB of memory on Intel Xeon Platinum 8259 (Cascade Lake) (up to 3.1 GHz), which makes it memory-heavy at 8 GiB of memory per vCPU.

Within the same generation and size, the r5a.12xlarge on AMD EPYC 7571 costs $2.71/hour, 32% less ($946 a month). The other variants are the r5.12xlarge at $3.02, the r5ad.12xlarge at $3.14 and the r5d.12xlarge at $3.46.

Running it in N. Virginia instead of Sydney saves $648 a month per instance: $4.01/hour against $4.90/hour, a 22% spread. It is not offered in Canada Central, São Paulo, London and Mumbai, so plan around that if you need a presence there.

On demand it costs $4.01/hour in US East (N. Virginia), $2,926 a month if left running, which puts it mid-table for memory optimized types at the 57th percentile per vCPU ($0.0835 per vCPU-hour) and the 73rd percentile per GiB ($0.0104 per GiB-hour).

It has local instance storage (2 x 900 GB NVMe SSD), which is fast but lost when the instance stops. Network: 50 Gigabit.

Looking beyond its own line, 23 of 40 current types with 48 vCPUs and similar memory are cheaper. The cheapest of those is the r6g.12xlarge on AWS Graviton2 at $2.42/hour.

Price by region (USD per hour)

RegionLinuxWindows1-yr RI3-yr RI
N. Virginia us-east-1$4.01$6.22$2.52$1.63
Ohio us-east-2$4.01$6.22$2.52$1.63
Oregon us-west-2$4.01$6.22$2.52$1.63
Ireland eu-west-1$4.46$6.67$2.81$1.87
Frankfurt eu-central-1$4.78$6.98$3.01$1.99
Singapore ap-southeast-1$4.80$7.01$3.02$1.97
Sydney ap-southeast-2$4.90$7.10$3.08$2.00
Tokyo ap-northeast-1$4.87$7.08$3.07$2.05

Shared tenancy, no pre-installed software. Reserved rates are standard, no upfront, per hour. Prices as of 2026-11-04.

Same shape, other types

TypevCPUMemory$/hourvs r5dn.12xlarge
r6g.12xlarge
AWS Graviton2 Processor
48384 GiB$2.42-40%
r7g.12xlarge
AWS Graviton3 Processor
48384 GiB$2.57-36%
r5a.12xlarge
AMD EPYC 7571
48384 GiB$2.71-32%
r6a.12xlarge
AMD EPYC 7R13 Processor
48384 GiB$2.72-32%
r6gd.12xlarge
AWS Graviton2 Processor
48384 GiB$2.76-31%
r8g.12xlarge
AWS Graviton4 Processor
48384 GiB$2.83-29%

Cost calculator

Specs

vCPU48
Memory384 GiB (8.0 per vCPU)
ProcessorIntel Xeon Platinum 8259 (Cascade Lake)
Clock3.1 GHz
Storage2 x 900 GB NVMe SSD
Network50 Gigabit

r5dn sizes

r5dn.large2 vCPU$0.1670
r5dn.xlarge4 vCPU$0.3340
r5dn.2xlarge8 vCPU$0.6680
r5dn.4xlarge16 vCPU$1.34
r5dn.8xlarge32 vCPU$2.67
r5dn.12xlarge48 vCPU$4.01
r5dn.16xlarge64 vCPU$5.34
r5dn.24xlarge96 vCPU$8.02