r5dn.16xlarge
Memory optimized · r5dn series · Intel Xeon Platinum 8259 (Cascade Lake)
- vCPU
- 64
- Memory
- 512 GiB
- Linux / hour
- $5.34
- Per month
- $3,901
- Per vCPU-hour
- $0.0835
- Per GiB-hour
- $0.0104
Analysis
The r5dn.16xlarge is a memory optimized instance in the r5dn series with 64 vCPUs and 512 GiB of memory on Intel Xeon Platinum 8259 (Cascade Lake) (up to 3.1 GHz), which makes it memory-heavy at 8 GiB of memory per vCPU.
Within the same generation and size, the r5a.16xlarge on AMD EPYC 7571 costs $3.62/hour, 32% less ($1,261 a month). The other variants are the r5.16xlarge at $4.03, the r5ad.16xlarge at $4.19 and the r5d.16xlarge at $4.61.
Running it in N. Virginia instead of Sydney saves $864 a month per instance: $5.34/hour against $6.53/hour, a 22% spread. It is not offered in Canada Central, São Paulo, London and Mumbai, so plan around that if you need a presence there.
Looking beyond its own line, 26 of 39 current types with 64 vCPUs and similar memory are cheaper. The cheapest of those is the r6g.16xlarge on AWS Graviton2 at $3.23/hour.
On demand it costs $5.34/hour in US East (N. Virginia), $3,901 a month if left running, which puts it mid-table for memory optimized types at the 57th percentile per vCPU ($0.0835 per vCPU-hour) and the 73rd percentile per GiB ($0.0104 per GiB-hour).
It has local instance storage (4 x 600 GB NVMe SSD), which is fast but lost when the instance stops. Network: 75 Gigabit.
Price by region (USD per hour)
| Region | Linux | Windows | 1-yr RI | 3-yr RI | |
|---|---|---|---|---|---|
| N. Virginia us-east-1 | $5.34 | $8.29 | $3.37 | $2.18 | |
| Ohio us-east-2 | $5.34 | $8.29 | $3.37 | $2.18 | |
| Oregon us-west-2 | $5.34 | $8.29 | $3.37 | $2.18 | |
| Ireland eu-west-1 | $5.95 | $8.90 | $3.75 | $2.49 | |
| Frankfurt eu-central-1 | $6.37 | $9.31 | $4.01 | $2.65 | |
| Singapore ap-southeast-1 | $6.40 | $9.34 | $4.03 | $2.63 | |
| Sydney ap-southeast-2 | $6.53 | $9.47 | $4.11 | $2.67 | |
| Tokyo ap-northeast-1 | $6.50 | $9.44 | $4.09 | $2.73 |
Shared tenancy, no pre-installed software. Reserved rates are standard, no upfront, per hour. Prices as of 2026-11-04.
Same shape, other types
| Type | vCPU | Memory | $/hour | vs r5dn.16xlarge |
|---|---|---|---|---|
| r6g.16xlarge AWS Graviton2 Processor | 64 | 512 GiB | $3.23 | -40% |
| r7g.16xlarge AWS Graviton3 Processor | 64 | 512 GiB | $3.43 | -36% |
| r5a.16xlarge AMD EPYC 7571 | 64 | 512 GiB | $3.62 | -32% |
| r6a.16xlarge AMD EPYC 7R13 Processor | 64 | 512 GiB | $3.63 | -32% |
| r6gd.16xlarge AWS Graviton2 Processor | 64 | 512 GiB | $3.69 | -31% |
| r8g.16xlarge AWS Graviton4 Processor | 64 | 512 GiB | $3.77 | -29% |
Cost calculator
Specs
| vCPU | 64 |
|---|---|
| Memory | 512 GiB (8.0 per vCPU) |
| Processor | Intel Xeon Platinum 8259 (Cascade Lake) |
| Clock | 3.1 GHz |
| Storage | 4 x 600 NVMe SSD |
| Network | 75 Gigabit |
r5dn sizes
| r5dn.large | 2 vCPU | $0.1670 |
| r5dn.xlarge | 4 vCPU | $0.3340 |
| r5dn.2xlarge | 8 vCPU | $0.6680 |
| r5dn.4xlarge | 16 vCPU | $1.34 |
| r5dn.8xlarge | 32 vCPU | $2.67 |
| r5dn.12xlarge | 48 vCPU | $4.01 |
| r5dn.16xlarge | 64 vCPU | $5.34 |
| r5dn.24xlarge | 96 vCPU | $8.02 |