r5n.12xlarge

Memory optimized · r5n series · Intel Xeon Platinum 8259 (Cascade Lake)

vCPU
48
Memory
384 GiB
Linux / hour
$3.58
Per month
$2,610
Per vCPU-hour
$0.0745
Per GiB-hour
$0.00931

Analysis

The r5n.12xlarge is a memory optimized instance in the r5n series with 48 vCPUs and 384 GiB of memory on Intel Xeon Platinum 8259 (Cascade Lake) (up to 2.5 GHz), which makes it memory-heavy at 8 GiB of memory per vCPU.

Within the same generation and size, the r5a.12xlarge on AMD EPYC 7571 costs $2.71/hour, 24% less ($631 a month). The other variants are the r5.12xlarge at $3.02, the r5ad.12xlarge at $3.14 and the r5d.12xlarge at $3.46.

Running it in N. Virginia instead of São Paulo saves $1,524 a month per instance: $3.58/hour against $5.66/hour, a 58% spread.

On demand it costs $3.58/hour in US East (N. Virginia), $2,610 a month if left running, which puts it mid-table for memory optimized types at the 40th percentile per vCPU ($0.0745 per vCPU-hour) and the 56th percentile per GiB ($0.00931 per GiB-hour).

Looking beyond its own line, 16 of 40 current types with 48 vCPUs and similar memory are cheaper. The cheapest of those is the r6g.12xlarge on AWS Graviton2 at $2.42/hour.

It is size 6 of 8 in the r5n series. Stepping up to the r5n.16xlarge gives 64 vCPUs and 512 GiB for $870 more a month. Dropping to the r5n.8xlarge saves $870 a month.

Price by region (USD per hour)

RegionLinuxWindows1-yr RI3-yr RI
N. Virginia us-east-1$3.58$5.78$2.25$1.45
Ohio us-east-2$3.58$5.78$2.25$1.45
Oregon us-west-2$3.58$5.78$2.25$1.45
Canada Central ca-central-1$3.91$6.12$2.47$1.52
São Paulo sa-east-1$5.66$7.87$3.57$2.33
Ireland eu-west-1$4.01$6.22$2.52$1.65
London eu-west-2$4.20$6.41$2.66$1.77
Frankfurt eu-central-1$4.27$6.48$2.69$1.76
Mumbai ap-south-1$3.67$5.88$2.31$1.49
Singapore ap-southeast-1$4.27$6.48$2.69$1.76
Sydney ap-southeast-2$4.34$6.55$2.74$1.76
Tokyo ap-northeast-1$4.34$6.55$2.74$1.79

Shared tenancy, no pre-installed software. Reserved rates are standard, no upfront, per hour. Prices as of 2026-11-04.

Same shape, other types

TypevCPUMemory$/hourvs r5n.12xlarge
r6g.12xlarge
AWS Graviton2 Processor
48384 GiB$2.42-32%
r7g.12xlarge
AWS Graviton3 Processor
48384 GiB$2.57-28%
r5a.12xlarge
AMD EPYC 7571
48384 GiB$2.71-24%
r6a.12xlarge
AMD EPYC 7R13 Processor
48384 GiB$2.72-24%
r6gd.12xlarge
AWS Graviton2 Processor
48384 GiB$2.76-23%
r8g.12xlarge
AWS Graviton4 Processor
48384 GiB$2.83-21%

Cost calculator

Specs

vCPU48
Memory384 GiB (8.0 per vCPU)
ProcessorIntel Xeon Platinum 8259 (Cascade Lake)
Clock2.5 GHz
StorageEBS only
Network50 Gigabit

r5n sizes

r5n.large2 vCPU$0.1490
r5n.xlarge4 vCPU$0.2980
r5n.2xlarge8 vCPU$0.5960
r5n.4xlarge16 vCPU$1.19
r5n.8xlarge32 vCPU$2.38
r5n.12xlarge48 vCPU$3.58
r5n.16xlarge64 vCPU$4.77
r5n.24xlarge96 vCPU$7.15